Cortical Reorganization Following Loss of Receptors

Principal mechanism of the cortical reorganization following loss of receptors

The removal of receptors deactivates their cortical sensory area as well as those regions of the brain to which it transmits information. The neighbouring active cortical sensory areas tend to involve the deactivated one in their activity. Part of their sensory input is redirected towards the deactivated area. Their neurons form a new connection with its neurons. The cortical reorganization following the loss of receptors eventually rewires, reactivates and reutilizes the deactivated sensory area and replaces its sensory input. The capacity of the brain to process the redirected input increases.